HPE ProLiant ML110 Gen10 Upgrade Guide
Maximize the performance and lifespan of your ProLiant ML110 Gen10 (Gen10). Every upgrade option below is verified compatible.
Next generation: ProLiant DL380 Gen10 Plus (Gen10 Plus)
Upgrade Storage
Moving from spinning disk to SSD or NVMe storage provides the largest single performance improvement — often 10-50x faster I/O. Consider NVMe for boot drives and high-IOPS workloads.

07N8808 147-GB ULTRA320 SCSI HP 10K

07N8818 73.4-GB ULTRA320 SCSI HP 10K

07N9418 147-GB ULTRA320 SCSI HP 10K

07N9428 73.4-GB ULTRA320 SCSI HP 10K

08K0293 Hitachi 36-GB ULTRA320 SCSI HP 10K

08K0312 36-GB ULTRA320 SCSI HP 10K
Upgrade Accessories
Rails, bezels, cable management arms, and drive caddies keep your server organized and serviceable. Replacing worn accessories extends the physical life of your equipment.

013224-001 HP 256MB BBWC Cache Module

05-50064-00 Broadcom U.2 Enabler Cable SFF-8643 to SFF-8639 1M

110936-B21 KVM Server Console Cable 12'

110936-B22 KVM Server Console Cable 20'

110936-B23 KVM Server Console Cable 40'

110936-B24 Compaq KVM Cable 3'
Upgrade Networking
Stepping up from 1GbE to 10GbE or 25GbE eliminates network bottlenecks for VM migration, iSCSI storage traffic, and backup windows. Most modern workloads benefit from at least 10GbE.

118042-001 HP PCI10 100 NIC Card

127552-B21 HP 8-PORT Fiber Channel Switch

127553-B21 HP 16-PORT Fibre Channel Switch

138603-B21 HP NC3134 NIC 64 PCI Dual Port 10/100

161105-001 HP NC3134 Dual NIC Card

161106-001 HP NC3135 Fast Ethernet Card
Upgrade Memory
Memory is the most impactful upgrade for virtualization and database workloads. Upgrading from 64GB to 128GB or 256GB can dramatically improve VM density and application response times.

590489-B21 HP CPU Memory Upgrade

5YZ54AT HPE 16GB RDIMM DDR4-2933 PC4-23400R ECC Memory

809085-091 HPE 64GB RDIMM DDR4-2666 PC4-21300R ECC Memory

809086-091 HPE 128GB LRDIMM DDR4-2666 PC4-21300L ECC Memory

809208-B21 HPE 128GB LRDIMM DDR4-2666 PC4-21300L ECC Memory

815097-B21 HPE 8GB RDIMM DDR4-2666 PC4-21300R ECC Memory
Upgrade Power & Cooling
This category provides verified compatible upgrade paths. ICD engineers validate every part for compatibility with your specific server model and workload requirements.

0HPX07 Dell Pe 495W Power Supply

122225-001 HP ML530 Redundant Fan Kit

122633-001 Fan: Fan - Chassis Fan 120MM 130CFM V/Speed 3BL

123482 HPE Storageworks Fan Module for M5314

123482-005 HP Fan Assembly

126310-001 HP Blower Module 2200 600
Upgrade Controllers
Upgrading your RAID controller enables faster disk I/O, larger cache, and support for newer drive technologies. Essential when adding NVMe or SAS-4 drives.

001 HP 4M Netraid Adapter 128MB

158223-B21 HP 16-PORT Fibre Channel Switch

176804-002 HP 1-GB 64-BIT PCI Fibre Channel

218382-001 HP HOT-PLUG Redundant Fan

250176-001 HP Fiber Channel Host

261329-B21 HP 2-GB 64-BIT PCI - FC
Upgrade Processors
CPU upgrades deliver more cores and higher clock speeds. If your workload is CPU-bound (compilation, analytics, HPC), upgrading from 8-core to 16+ core processors provides significant throughput improvement.

001 HP 4M Netraid Adapter 128MB

120672-B21 Genuine HP

120673-B21 HP ProLiant Server Option Kit

123482-005 HP Fan Assembly

123958-001 HP ProLiant Server Component

144007-001 Genuine HP
More ProLiant ML110 Gen10 Resources
Ready to upgrade your ProLiant ML110 Gen10?
Tell us your current configuration and workload. Our engineers will recommend the most impactful upgrades with guaranteed compatibility.
Get Upgrade Quote